Purpose Driven Research
Genetic Disease Investigators LLC, Diana Driscoll, OD, President, is a global leader in autonomic research. The first to identify abnormalities of parasympathetic nerves (such as the vagus nerve), vascular problems, and intracranial pressure abnormalities, Genetic Disease Investigators LLC continues to release answers — years in advance of others.
Help us get answers! Sign up for a study today!
If you are a chronic dry eye patient interested in new treatments, we invite you to participate in these studies:
Dry Eye Survey:
Complete this 3-minute survey to see if your dry eyes could be more than just an “eye problem”.
Dry Eye Treatment Study
This exciting new study will be treating dry eyes using NeuroTears. This ground-breaking research uses a patented over-the-counter supplement to stimulate both inflammation control and tear production simultaneously. Please let us know if you are interested and we will reach out to you to see if you qualify.
COVID and the Vagus Nerve – An amazing discovery
The vagus nerve is affected in post-COVID Longhaulers! This contributes to dysautonomia (dysfunction of parts of the autonomic nervous system)
Do you need to stimulate your vagus nerve?
The vagus nerve is the major nerve controlling the parasympathetic nervous system – the system of the body that allows us to
Vascular fundus changes in patients with high probability of chronic cerebrospinal venous insufficiency
Presented February 2012- International Society of Neurovascular Disease. This study included co-authors Dr. Clair Francomano and Diana Driscoll, OD and involved the evaluation of 60 fundus images of patients with EDS/POTS or multiple sclerosis, as compared to age-matched normals. The vascular abnormalities found allowed a “blinded” doctor to correctly identify patients with EDS/POTS with 90%...
Acetazolomide as a medical treatment option for patients with neurodegenerative disease
Presented February 2012 — International Society of Neurovascular Disease This study, co-authored by Dr. William Code and Diana Driscoll, OD revealed the improvement of symptoms of headache, poor sleep, fatigue and cognition in patients with multiple sclerosis with the use of acetazolamide. Although likely multifactorial, undiagnosed idiopathic intraocular hypertension (“IIH”) as a likely cause...
Cardiac effects in the multiple sclerosis patient
Presented February 2012: International Society Neurovascular Disease This study, co-authored by Dr. Clair Francomano and Diana Driscoll, OD began the study of the potential role of inflammatory cytokines in the development of left ventricular diastolic dysfunction typically found in both multiple sclerosis and Ehlers-Danlos syndrome patients. By evaluating similarities and differences in these...
Vascular fundus changes in patients with high probability of chronic cerebrospinal venous insufficiency
June 2012- Optometry’s Meeting Clinicaltrials.org NCT#01356134 This study included co-authors Dr. Clair Francomano and Diana Driscoll, OD and involved the evaluation of 60 fundus images of patients with EDS/POTS or multiple sclerosis, as compared to age-matched normals. The vascular abnormalities found allowed a “blinded” doctor to correctly identify patients with EDS/POTS with 90% accuracy. The...
Head circumference growth in children with Ehlers-Danlos syndrome who developed dysautonomia later in life
Clinicaltrials.org NCT#01367977 Preliminary results of this study revealed abnormally fast growth of head circumferences (as opposed to the lengths and weights) in babies who were later diagnosed with EDS (“Ehlers-Danlos syndrome”) / POTS (“Postural Orthostatic Tachycardia Syndrome”). Enlarged head circumferences as found by this study hinted at, yet could not prove, the presence of high...
Inflammatory cytokines in patients with EDS / POTS / Dysautonomia
An in-house study of inflammatory cytokines in EDS / POTS / Dysautonomia patients revealed the involvement of inflammation in many of these patients, dramatically altering the approach to evaluation and treatment.
Evaluation of lipo(a) in patients with vascular fibrosis and EDS/POTS/Dysautonomia
An in-house study of six patients with EDS / POTS / Dysautonomia and vascular fibrosis run to find out if abnormal lipo(a) was the cause of their vascular abnormalities. Normal levels were found, so research quickly moved in other directions.
Evaluation of potential IIHWOP in patients with EDS/POTS/Dysautonomia and treatments with acetazolamide, if indicated
An in-house study of 21 patients with EDS / POTS / Dysautonomia, studying the potential involvement of IIH (Idiopathic Intracranial Hypertension) or IIHWOP (Idiopathic Intracranial Hypertension Without Papilledema), and the effect of acetazolamide (Diamox) on symptoms.